Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop

Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop

Chrysin is a natural flavonoid with powerful neuroprotective capacity. Cerebral ischemia/reperfusion injury (CIRI) is associated with oxidative stress and ferroptosis. Hypoxia-inducible factor 1α (HIF-1α) and ceruloplasmin (CP) are the critical targets for oxidation reactions and iron transport. But...

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Bibliographic Details
Main Authors: Jinfeng Shang, Jiakang Jiao, Jingyi Wang, Mingxue Yan, Qiannan Li, Lizha Shabuerjiang, Guijinfeng Huang, Qi Song, Yinlian Wen, Xiaolu Zhang, Kai Wu, Yiran Cui, Xin Liu
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Chrysin
Cerebral ischemia/reperfusion injury (CIRI)
Ferroptosis
HIF-1α/CP loop
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224003846

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http://www.sciencedirect.com/science/article/pii/S0753332224003846

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