A Novel Antibiotic, Rhodomyrtone: Pharmacokinetic Studies in a Murine Model and Optimization and Validation of High-Performance Liquid Chromatographic Method for Plasma Analysis

Rhodomyrtone has indisputable and undeniable potential as a new antibiotic for antibiotic-resistant Gram-positive bacteria. Therefore, the main objective of this study was to determine the pharmacokinetics profiles of orally administered rhodomyrtone in rats. A reverse-phase HPLC-UV method was devel...

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Bibliographic Details
Main Authors: Tan Suwandecha, Boon-Ek Yingyongnarongkul, Kanokkan Towtawin, Supayang Piyawan Voravuthikunchai, Somchai Sriwiriyajan
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/13/2/156