Construction of fibronectin conditional gene knock-out mice and the effect of fibronectin gene knockout on hematopoietic, biochemical and immune parameters in mice

Fibronectin (FN) is a multi-functional glycoprotein that primarily acts as a cell adhesion molecule and tethers cells to the extra cellular matrix. In order to clarify the effect of FN deficiency on hematopoiesis, biochemical and immune parameters in mice. We constructed a tamoxifen-induced conditio...

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Bibliographic Details
Main Authors: Xiaohong Yuan, Shu Yang, Wen Li, Jinggang Li, Jia Lin, Yong Wu, Yuanzhong Chen
Format: Article
Language:English
Published: PeerJ Inc. 2020-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10224.pdf