Quantitative Structure–Activity Relationship Analysis of Isosteviol-Related Compounds as Activated Coagulation Factor X (FXa) Inhibitors

Quantitative Structure–Activity Relationship Analysis of Isosteviol-Related Compounds as Activated Coagulation Factor X (FXa) Inhibitors

Stevioside, one of the natural sweeteners extracted from stevia leaves, and its derivatives are considered to have numerous beneficial pharmacological properties, including the inhibition of activated coagulation factor X (FXa). FXa-PAR signaling is a possible therapeutic target to enhance impaired...

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Bibliographic Details
Main Authors: Marcin Gackowski, Karolina Szewczyk-Golec, Katarzyna Mądra-Gackowska, Robert Pluskota, Marcin Koba
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Nutrients
Subjects:
isosteviol derivatives
diabetes
FXa inhibitors
multivariate adaptive regressions splines
obesity
quantitative structure–activity relationships (QSAR)
Online Access:https://www.mdpi.com/2072-6643/14/17/3521

Internet

https://www.mdpi.com/2072-6643/14/17/3521

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