Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity

Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity

In this study, we have shown that a paraneoplastic cerebellar degeneration (PCD)-associated antigen, pcd17, binds to a cell cycle-related protein, MRG15. MRG15 derepresses the E2F-responsive B-myb promoter. The pcd17 antigen inhibits the derepression of the B-myb transcriptional activity by MRG15, a...

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Bibliographic Details
Main Authors: Koichiro Sakai, Yoko Kitagawa, Shinji Saiki, Misuzu Saiki, Genjiro Hirose
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Neurobiology of Disease
Subjects:
B-myb
Cerebellar degeneration
Purkinje cell
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103002407

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http://www.sciencedirect.com/science/article/pii/S0969996103002407

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