Using bioinformatics analysis to screen abnormal methylated differentially expressed hub genes of Kawasaki disease and construct diagnostic model

Using bioinformatics analysis to screen abnormal methylated differentially expressed hub genes of Kawasaki disease and construct diagnostic model

Objective: By using bioinformatics analysis, abnormal methylated differentially expressed genes (MDEGs) in Kawasaki disease (KD) were identified and a random forest diagnostic model for KD was established. Methods: The expression (GSE18606, GSE68004, GSE73461) and methylation (GSE109430) profiles wa...

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Bibliographic Details
Main Authors: Hongxiao Sun, Changying Liu, Xu Zhang, Panpan Liu, Zhanhui Du, Gang Luo, Silin Pan
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Differentially expressed genes
Gene expression omnibus
Kawasaki disease
Protein-protein interaction network
Random forest
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022031930

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http://www.sciencedirect.com/science/article/pii/S2405844022031930

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