The Parameter-Fitness Landscape of <italic toggle="yes">lexA</italic> Autoregulation in <named-content content-type="genus-species">Escherichia coli</named-content>

The Parameter-Fitness Landscape of <italic toggle="yes">lexA</italic> Autoregulation in <named-content content-type="genus-species">Escherichia coli</named-content>

ABSTRACT Feedback mechanisms are fundamental to the control of physiological responses. One important example in gene regulation, termed negative autoregulation (NAR), occurs when a transcription factor (TF) inhibits its own production through transcriptional repression. This enables more-rapid home...

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Bibliographic Details
Main Authors: Beverley C. Kozuch, Marla G. Shaffer, Matthew J. Culyba
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSphere
Subjects:
DNA damage
LexA
SOS response
autoregulation
feedback
transcription regulation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00718-20

Internet

https://journals.asm.org/doi/10.1128/mSphere.00718-20

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