Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated PyroptosisSummary

Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated PyroptosisSummary

Background: Pyroptosis, gasdermin-mediated programmed cell death, is readily induced in macrophages by activation of the canonical inflammasome (caspase-1) or by intracellular lipopolysaccharide (LPS)-mediated non-canonical inflammasome (caspase-11) activation. However, whether pyroptosis is induced...

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Bibliographic Details
Main Authors: Ping Sun, Jie Zhong, Hong Liao, Patricia Loughran, Joud Mulla, Guang Fu, Da Tang, Jie Fan, Timothy R. Billiar, Wentao Gao, Melanie J. Scott
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Liver Disease
Caspase-1
Caspase-11
Gasdermin-D
Programmed Cell Death
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21002472

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http://www.sciencedirect.com/science/article/pii/S2352345X21002472

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