Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies
Abstract A candidate multigenic SARS-CoV-2 vaccine based on an MVA vector expressing both viral N and S proteins (MVA-S + N) was immunogenic, and induced T-cell responses and binding antibodies to both antigens but in the absence of detectable neutralizing antibodies. Intranasal immunization with th...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-11-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-021-00405-5 |