Potential and limitations of PKA/ PKG inhibitors for platelet studies

Potential and limitations of PKA/ PKG inhibitors for platelet studies

Cyclic nucleotides (cAMP and cGMP) and corresponding protein kinases, protein kinase A (PKA) and protein kinase G (PKG), are the main intracellular mediators of endothelium-derived platelet inhibitors. Pharmacological PKA/PKG inhibitors are often used to discriminate between these two kinase activit...

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Bibliographic Details
Main Authors: Valentina Shpakova, Natalia Rukoyatkina, Ulrich Walter, Stepan Gambaryan
Format: Article
Language:English
Published: Taylor & Francis Group 2022-08-01
Series:Platelets
Subjects:
camp
cgmp
pka
pkg inhibitors
platelet
Online Access:http://dx.doi.org/10.1080/09537104.2021.2003316

Internet

http://dx.doi.org/10.1080/09537104.2021.2003316

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