The effects of the NMDAR co-agonist d-serine on the structure and function of optic tectal neurons in the developing visual system

Abstract The N-methyl-d-aspartate type glutamate receptor (NMDAR) is a molecular coincidence detector which converts correlated patterns of neuronal activity into cues for the structural and functional refinement of developing circuits in the brain. d-serine is an endogenous co-agonist of the NMDAR....

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Bibliographic Details
Main Authors: Zahraa Chorghay, Vanessa J. Li, Anne Schohl, Arna Ghosh, Edward S. Ruthazer
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39951-4