CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock.

CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock.

Intracellular circadian clocks, composed of clock genes that act in transcription-translation feedback loops, drive global rhythmic expression of the mammalian transcriptome and allow an organism to anticipate to the momentum of the day. Using a novel clock-perturbing peptide, we established a pivot...

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Bibliographic Details
Main Authors: Teruya Tamaru, Mitsuru Hattori, Kousuke Honda, Yasukazu Nakahata, Paolo Sassone-Corsi, Gijsbertus T J van der Horst, Takeaki Ozawa, Ken Takamatsu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002293

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https://doi.org/10.1371/journal.pbio.1002293

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