Omicron’s binding to sotrovimab, casirivimab, imdevimab, CR3022, and sera from previously infected or vaccinated individuals

Omicron’s binding to sotrovimab, casirivimab, imdevimab, CR3022, and sera from previously infected or vaccinated individuals

Summary: SARS-CoV-2 Omicron is the first pandemic variant of concern exhibiting an abrupt accumulation of mutations particularly in the receptor-binding domain that is a critical target of vaccination induced and therapeutic antibodies. Omicron's mutations did only marginally affect the binding...

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Bibliographic Details
Main Authors: Anna-Lena Mader, Leonid Tydykov, Vivian Glück, Manuela Bertok, Tanja Weidlich, Christine Gottwald, Alexa Stefl, Matthias Vogel, Annelie Plentz, Josef Köstler, Bernd Salzberger, Jürgen J. Wenzel, Hans Helmut Niller, Jonathan Jantsch, Ralf Wagner, Barbara Schmidt, Thomas Glück, André Gessner, David Peterhoff
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:iScience
Subjects:
Health sciences
Medicine
Immunology
Biological sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222003467

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222003467

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