Reverse phase, ion exchange, HILIC and mix-mode chromatography for the determination of metformin and evogliptin in human plasma and pharmaceutical formulations

Separation and quantification of highly polar metformin (MTF) alone or in combination with dipeptidyl peptidase-4 inhibitors, such as evogliptin (EVG), sitagliptin, saxagliptin, vildagliptin, linagliptin and teneligliptin, specifically from human plasma and pharmaceutical products is still difficult...

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Main Authors: Pankaj M. Kharabe, Prasad P. Jumade, Pravin N. Khatale, Parimal P. Katolkar, Santosh R. Butle, Mahendra D. Kshirsagar, Vishal V. Pendharkar, Amol V. Sawale, Kalyani S. Choudhari
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Talanta Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666831923000942