A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol

A natural history study to track brain and spinal cord changes in individuals with Friedreich’s ataxia: TRACK-FA study protocol

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<h4>Introduction</h4> Drug development for neurodegenerative diseases such as Friedreich’s ataxia (FRDA) is limited by a lack of validated, sensitive biomarkers of pharmacodynamic response in affected tissue and disease progression. Studies employing neuroimaging measures to track FRDA h...

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Main Authors: Nellie Georgiou-Karistianis, Louise A. Corben, Kathrin Reetz, Isaac M. Adanyeguh, Manuela Corti, Dinesh K. Deelchand, Martin B. Delatycki, Imis Dogan, Rebecca Evans, Jennifer Farmer, Marcondes C. França, William Gaetz, Ian H. Harding, Karen S. Harris, Steven Hersch, Richard Joules, James J. Joers, Michelle L. Krishnan, Michelle Lax, Eric F. Lock, David Lynch, Thomas Mareci, Sahan Muthuhetti Gamage, Massimo Pandolfo, Marina Papoutsi, Thiago J. R. Rezende, Timothy P. L. Roberts, Jens T. Rosenberg, Sandro Romanzetti, Jörg B. Schulz, Traci Schilling, Adam J. Schwarz, Sub Subramony, Bert Yao, Stephen Zicha, Christophe Lenglet, Pierre-Gilles Henry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678384/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9678384/?tool=EBI

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