A New Pentacyclic Triterpene from Humata tyermanni Moore with the Inhibitory Activities against LPS-Induced NO Production in RAW264.7 Macrophages

One new pentacyclic triterpene, hopane-22 (29)-en-24ol (2), with five known hopane-type pentacyclic triterpene compounds: hop-22(29)-ene (1), adiantone (3), 22-hydroxyhopane (4), 6α, 22-dihydroxyhopane (5), and 17(21)-hopene (6) were isolated from Humata tyermanni Moore. The structure of compound 2...

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Бібліографічні деталі
Автори: Lei Zhang, Feng Wang, Zhen-You Jiang, Yao-Kui Zhu, Ying-Zhou Cen
Формат: Стаття
Мова:English
Опубліковано: Hindawi Limited 2013-01-01
Серія:Journal of Chemistry
Онлайн доступ:http://dx.doi.org/10.1155/2013/727136
Опис
Резюме:One new pentacyclic triterpene, hopane-22 (29)-en-24ol (2), with five known hopane-type pentacyclic triterpene compounds: hop-22(29)-ene (1), adiantone (3), 22-hydroxyhopane (4), 6α, 22-dihydroxyhopane (5), and 17(21)-hopene (6) were isolated from Humata tyermanni Moore. The structure of compound 2 was elucidated on the basis of its 1D and 2D NMR spectral analysis. All these compounds were evaluated for their inhibitory activities of LPS-induced nitric oxide (NO) production in RAW264.7 macrophages.
ISSN:2090-9063
2090-9071