Epiregulin expression and secretion is increased in castration-resistant prostate cancer

Epiregulin expression and secretion is increased in castration-resistant prostate cancer

IntroductionIn prostate cancer, long-term treatment directed against androgens often leads to the development of metastatic castration-resistant prostate cancer, which is more aggressive and not curatively treatable. Androgen deprivation results in elevated epiregulin expression in LNCaP cells which...

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Bibliographic Details
Main Authors: Marc Wiesehöfer, Benedikt Bernhard Gereon Raczinski, Caroline Wiesehöfer, Jaroslaw Thomas Dankert, Elena Dilara Czyrnik, Martin Spahn, Marianna Kruithof-de Julio, Gunther Wennemuth
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
castration-resistant prostate cancer
enzalutamide-resistant LNCaP cells
epiregulin (EREG)
epiregulin biosynthesis
miRNA-19
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1107021/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1107021/full

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