Intracranial Pressure Elevation 24 Hours after Ischemic Stroke in Aged Rats is Prevented by Early, Short Hypothermia Treatment

Intracranial Pressure Elevation 24 Hours after Ischemic Stroke in Aged Rats is Prevented by Early, Short Hypothermia Treatment

Stroke is predominantly a senescent disease, yet most preclinical studies investigate treatment in young animals. We recently demonstrated that short-duration hypothermia-treatment completely prevented the dramatic intracranial pressure (ICP) rise seen post-stroke in young rats. Here, our aim was to...

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Bibliographic Details
Main Authors: Lucy Anne Murtha, Daniel Joseph Beard, Julia eBourke, Debbie ePepperall, Damian Donald McLeod, Neil James Spratt
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Intracranial Pressure
cerebral edema
middle cerebral artery occlusion
ischaemic stroke
Aged rats
Therapuetic Hypothermia
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00124/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00124/full

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