Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes

Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes

Members of the fetal-gene-program may act as regulatory components to impede deleterious events occurring with cardiac remodeling, and constitute potential novel therapeutic heart failure (HF) targets. Mitochondrial energy derangements occur both during early fetal development and in patients with H...

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Bibliographic Details
Main Authors: Nils Bomer, Mario G. Pavez-Giani, Frederik E. Deiman, Annet N. Linders, Martijn F. Hoes, Christiane L.J. Baierl, Silke U. Oberdorf-Maass, Rudolf A. de Boer, Herman H.W. Silljé, Eugene Berezikov, Warner S. Simonides, B. Daan Westenbrink, Peter van der Meer
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
heart failure
selenoproteins
DIO2
human cardiomyocytes
mtUPR
mitochondrial function
Online Access:https://www.mdpi.com/1422-0067/22/21/11906

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https://www.mdpi.com/1422-0067/22/21/11906

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