Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model

Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding Nav1.6) are associated with a spectrum of clinical presentation, including multiple seizure types, movement disorders, intellectual disability, and behavioral abnormaliti...

Full description

Bibliographic Details
Main Authors: Lindsey Shapiro, Andrew Escayg, Jennifer C. Wong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.815950/full