Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding Nav1.6) are associated with a spectrum of clinical presentation, including multiple seizure types, movement disorders, intellectual disability, and behavioral abnormaliti...
Main Authors: | Lindsey Shapiro, Andrew Escayg, Jennifer C. Wong |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-01-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.815950/full |
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