Pulsed Radiofrequency Upregulates Serotonin Transporters and Alleviates Neuropathic Pain-Induced Depression in a Spared Nerve Injury Rat Model

Pulsed Radiofrequency Upregulates Serotonin Transporters and Alleviates Neuropathic Pain-Induced Depression in a Spared Nerve Injury Rat Model

Neuropathic pain (NP) is difficult to treat due to complex pathophysiological mechanisms. Pulsed radiofrequency (RRF) has been used widely with neuromodulation effect in refractory chronic pain treatment. A recent study found that PRF treatment may decrease chronic pain-related anxiety-depressant sy...

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Bibliographic Details
Main Authors: Kuo-Hsing Ma, Cheng-Yi Cheng, Wei-Hung Chan, Shih-Yu Chen, Li-Ting Kao, Chun-Sung Sung, Dueng-Yuan Hueng, Chun-Chang Yeh
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Biomedicines
Subjects:
pulsed radiofrequency
neuropathic pain
depression-like behaviors
positron emission tomography
serotonin transporters
Online Access:https://www.mdpi.com/2227-9059/9/10/1489

Internet

https://www.mdpi.com/2227-9059/9/10/1489

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