Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease

Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease

Cell death and synapse dysfunction are two likely causes of cognitive decline in AD. As cells die and synapses lose their drive, remaining cells suffer an initial decrease in activity. Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity. This homeostatic mec...

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Bibliographic Details
Main Authors: Mark eRowan, Sam eNeymotin, William eLytton
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Computational Neuroscience
Subjects:
Homeostasis
Neocortex
Alzheimer's disease
synaptic scaling
neuroprosthetics
neuronal networks
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00039/full

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http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00039/full

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