Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease
Cell death and synapse dysfunction are two likely causes of cognitive decline in AD. As cells die and synapses lose their drive, remaining cells suffer an initial decrease in activity. Neuronal homeostatic synaptic scaling then provides a feedback mechanism to restore activity. This homeostatic mec...
Main Authors: | Mark eRowan, Sam eNeymotin, William eLytton |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-04-01
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Series: | Frontiers in Computational Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncom.2014.00039/full |
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