Large-Scale Integration of Single-Cell RNA-Seq Data Reveals Astrocyte Diversity and Transcriptomic Modules across Six Central Nervous System Disorders

Large-Scale Integration of Single-Cell RNA-Seq Data Reveals Astrocyte Diversity and Transcriptomic Modules across Six Central Nervous System Disorders

The dysfunction of astrocytes in response to environmental factors contributes to many neurological diseases by impacting neuroinflammation responses, glutamate and ion homeostasis, and cholesterol and sphingolipid metabolism, which calls for comprehensive and high-resolution analysis. However, sing...

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Bibliographic Details
Main Authors: Zhenwei Qian, Jinglin Qin, Yiwen Lai, Chen Zhang, Xiannian Zhang
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
astrocytes
CNS disorder
scRNA-seq
spatial transcriptomics
transcriptomic modules
cell–cell communications
Online Access:https://www.mdpi.com/2218-273X/13/4/692

Internet

https://www.mdpi.com/2218-273X/13/4/692

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