Epigenetic landscape of 5-hydroxymethylcytosine and associations with gene expression in placenta

ABSTRACT5-hydroxymethylcystosine (5hmC), is an intermediate product in the DNA demethylation pathway, but may act as a functional epigenetic modification. We have conducted the largest study of site-specific 5hmC in placenta to date using parallel bisulphite and oxidative bisulphite modification wit...

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Bibliographic Details
Main Authors: Michael Mortillo, Elizabeth M. Kennedy, Karen E. Hermetz, Amber A. Burt, Carmen J. Marsit
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2326869