Stereochemistry of <i>N</i>-Acyl-5<i>H</i>-dibenzo[<i>b</i>,<i>d</i>]azepin-7(6<i>H</i>)-ones

Stereochemistry of <i>N</i>-Acyl-5<i>H</i>-dibenzo[<i>b</i>,<i>d</i>]azepin-7(6<i>H</i>)-ones

The stereochemical properties of <i>N</i>-acyl-5<i>H</i>-dibenzo[<i>b</i>,<i>d</i>]azepin-7(6<i>H</i>)-ones (<b>2a</b>–<b>c</b>), which inhibit potassium channels in T cells, were examined by freezing their conformat...

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Bibliographic Details
Main Authors: Arisa Chiba, Ryoko Tanaka, Mayuno Hotta, Kayo Nakamura, Kosho Makino, Hidetsugu Tabata, Tetsuta Oshitari, Hideaki Natsugari, Hideyo Takahashi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
axial chirality
atropisomer
dibenzoazepinone
Kv1.3
Online Access:https://www.mdpi.com/1420-3049/28/12/4734

Internet

https://www.mdpi.com/1420-3049/28/12/4734

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