Association of Augmented Immune-Staining of G-Quadruplex Tertiary DNA Structure in Chemo-Tolerant TNBC with Downregulation of WNT/Epidermal Growth Factor Receptor Pathway receptor Genes: A Pilot Clinicopathological Study

Association of Augmented Immune-Staining of G-Quadruplex Tertiary DNA Structure in Chemo-Tolerant TNBC with Downregulation of WNT/Epidermal Growth Factor Receptor Pathway receptor Genes: A Pilot Clinicopathological Study

Purpose: The aim of the study is to understand the involvement of G-Quadruplex (G-Q) structures in altering the expression profile of WNT/epidermal growth factor receptor (EGFR) pathway receptor genes in chemo-tolerant Triple Negative Breast Cancer (TNBC) samples. Materials and Methods: At first, Ge...

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Bibliographic Details
Main Authors: Saimul Islam, Mukta Basu, Anup Roy, Neyaz Alam, Chinmay Kumar Panda
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Radiation and Cancer Research
Subjects:
g-quadruplex structure
neoadjuvant chemotherapy
poor prognosis
triple-negative breast cancer
Online Access:http://www.journalrcr.org/article.asp?issn=2588-9273;year=2023;volume=14;issue=1;spage=14;epage=20;aulast=Islam

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http://www.journalrcr.org/article.asp?issn=2588-9273;year=2023;volume=14;issue=1;spage=14;epage=20;aulast=Islam

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