Expression of p16 in Colorectal Cancer and its Comparison with Prognostic Parameters
Aim: The cells are either in dividing or resting state. p 16 INK4a, arrests the cell cycle in late period of G1 stage, by inhibiting RB phosphorylation. The studies in recent years have shown that, in 30-50% of colorectal cancer, CpG portion of promoter region of p16 gene is hypermethylated. In...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2010-03-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://www.hasekidergisi.com/makale_4410/Kolorektal-Kanserlerde-P16-Ekspresyonu-Ve-Prognostik-Parametrelerle-Karsilastirilmasi-Ozgun-Arastirma |