Mechanism of m6A methyltransferase 3 in the pathogenesis of diabetic cataract

Mechanism of m6A methyltransferase 3 in the pathogenesis of diabetic cataract

AIM: To investigate the role and mechanism of N6-methyladenosine(m6A)methyltransferase 3(METTL3)in the pathogenesis of diabetic cataract.METHODS: We cultured SRA01/04 cells in low and high sugar media for 24h and measured changes in epithelial-mesenchymal transition(EMT)indicators(E-Cadherin, N-Cadh...

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Bibliographic Details
Main Authors: Si Chen, Wei Ye, Yun Tang, Wen-Zhe Wang, Yi-Rui Ge, Xue-Ying Wang, Zhen-Ping Huang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2023-08-01
Series:Guoji Yanke Zazhi
Subjects:
diabetic cataract
methyltransferase 3(mettl3)
n6-methyladenosine(m6a)
epithelial-mesenchymal transition
Online Access:http://ies.ijo.cn/cn_publish/2023/8/202308003.pdf

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http://ies.ijo.cn/cn_publish/2023/8/202308003.pdf

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