Connexin 43 trafficking and regulation of gap junctional intercellular communication alters ovarian cancer cell migration and tumorigenesis

Connexin 43 trafficking and regulation of gap junctional intercellular communication alters ovarian cancer cell migration and tumorigenesis

Ovarian cancer persists to be the most lethal gynecological malignancy, demanding rigorous treatments involving radio-chemotherapy that trigger toxicity and consequently mortality among patients. An improved understanding of the disease progression may pioneer curative therapies. Mouse epithelial ov...

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Bibliographic Details
Main Authors: Vaishali Mulchandani, Anurag Banerjee, Arunima Vijaya Vadlamannati, Saurav Kumar, Jayasri Das Sarma
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Syngeneic Ovarian cancer mouse model
ID8 and ID8 over-expressing Vascular Endothelial Growth Factor (VEGF) cell line
ID8-VEGF
Gap Junctional Intercellular Communication (GJIC) protein Connexin 43/Cx43
4-Phenylbutyrate (4PBA)
Migration and Tumorigenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223000847

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