Evaluation of a new ELISA assay for monoclonal free‐light chain detection in patients with cardiac amyloidosis

Evaluation of a new ELISA assay for monoclonal free‐light chain detection in patients with cardiac amyloidosis

Abstract The causal protein of amyloid light‐chain (AL) amyloidosis is a monoclonal immunoglobulin free light chain (mFLC), which must be quantified in the serum for patient diagnosis and monitoring. Several manufacturers commercialize immunoassays that quantify total kappa (κ) and lambda (λ) FLC, b...

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Bibliographic Details
Main Authors: Hajer Abroud, Asma Beldi‐Ferchiou, Vincent Audard, François Lemonnier, Fabien Le Bras, Karim Belhadj, Anissa Moktefi, Elsa Poullot, Khalil El Karoui, Jehan Dupuis, Alizée Maarek, Louise Roulin, Marie‐Hélène Delfau‐Larue, Silvia Oghina, Mounira Kharoubi, Mélanie Bézard, Amira Zaroui, Thibaud Damy, Valérie Molinier‐Frenkel
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:eJHaem
Subjects:
AL amyloidosis
cardiac amyloidosis
ELISA
free‐light chain
monoclonal gammopathy
Online Access:https://doi.org/10.1002/jha2.516

Internet

https://doi.org/10.1002/jha2.516

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