Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells

Summary: The Retinoid inducible nuclear factor (Rinf), also known as CXXC5, is a nuclear protein, but its functions in the context of the chromatin are poorly defined. We find that in mouse embryonic stem cells (mESCs), Rinf binds to the chromatin and is enriched at promoters and enhancers of Tet1,...

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Main Authors: Mirunalini Ravichandran, Run Lei, Qin Tang, Yilin Zhao, Joun Lee, Liyang Ma, Stephanie Chrysanthou, Benjamin M. Lorton, Ales Cvekl, David Shechter, Deyou Zheng, Meelad M. Dawlaty
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719309842

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http://www.sciencedirect.com/science/article/pii/S2211124719309842

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