The latent HIV reservoir: current advances in genetic sequencing approaches

The latent HIV reservoir: current advances in genetic sequencing approaches

ABSTRACT Multiple cellular HIV reservoirs in diverse anatomical sites can undergo clonal expansion and persist for years despite suppressive antiretroviral therapy, posing a major barrier toward an HIV cure. Commonly adopted assays to assess HIV reservoir size mainly consist of PCR-based measures of...

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Bibliographic Details
Main Authors: Preeti Moar, Thomas A. Premeaux, Andrew Atkins, Lishomwa C. Ndhlovu
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
HIV persistence
latency
DNA
RNA
virus
antiretroviral therapy
Online Access:https://journals.asm.org/doi/10.1128/mbio.01344-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01344-23

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