Methylcholanthrene-Induced Sarcomas Develop Independently from NOX2-Derived ROS.

Reactive oxygen species (ROS) produced by the inducible NADPH oxidase type 2 (NOX2) complex are essential for clearing certain infectious organisms but may also have a role in regulating inflammation and immune response. For example, ROS is involved in myeloid derived suppressor cell (MDSC)- and reg...

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Bibliographic Details
Main Authors: Maarten A Ligtenberg, Özcan Çınar, Rikard Holmdahl, Dimitrios Mougiakakos, Rolf Kiessling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0129786