Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model

<p>Abstract</p> <p>Uncovering the mechanisms that regulate dendritic spine morphology has been limited, in part, by the lack of efficient and unbiased methods for analyzing spines. Here, we describe an automated 3D spine morphometry method and its application to spine remodeling in...

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Bibliographic Details
Main Authors: Swanger Sharon A, Yao Xiaodi, Gross Christina, Bassell Gary J
Format: Article
Language:English
Published: BMC 2011-10-01
Series:Molecular Brain
Subjects:
Online Access:http://www.molecularbrain.com/content/4/1/38