Response surface based optimization of system variables for liquid chromatographic analysis of candesartan cilexetil

A statistical optimization method was successfully employed to study the effect of system variables on the chromatographic analysis of candesartan cilexetil. The effect of simultaneously varying the flow rate, temperature and concentration of acetonitrile in the mobile phase in water (0.05% O-phosph...

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Bibliographic Details
Main Authors: Jagdish V. Manwar, Snehal S. Vispute, Dipak D. Kumbhar, Rahul S. Manmode, Ravindra L. Bakal, Rajesh G. Jadhao, Shreyas D. Jogdand
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Journal of Taibah University for Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1658365516000078