Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria

Treating cell lines with glucocorticoids offers protection against the damage caused by subsequent exposure to selected bacterial pore-forming toxins, and is dependent on the glucocorticoid receptor.

Bibliographic Details
Main Authors: Thomas J. R. Ormsby, Sian E. Owens, Matthew L. Turner, James G. Cronin, John J. Bromfield, I. Martin Sheldon
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04568-w
_version_ 1797863794783813632
author Thomas J. R. Ormsby
Sian E. Owens
Matthew L. Turner
James G. Cronin
John J. Bromfield
I. Martin Sheldon
author_facet Thomas J. R. Ormsby
Sian E. Owens
Matthew L. Turner
James G. Cronin
John J. Bromfield
I. Martin Sheldon
author_sort Thomas J. R. Ormsby
collection DOAJ
description Treating cell lines with glucocorticoids offers protection against the damage caused by subsequent exposure to selected bacterial pore-forming toxins, and is dependent on the glucocorticoid receptor.
first_indexed 2024-04-09T22:41:21Z
format Article
id doaj.art-37c56c1d42024598a0cbc0976eec8687
institution Directory Open Access Journal
issn 2399-3642
language English
last_indexed 2024-04-09T22:41:21Z
publishDate 2023-02-01
publisher Nature Portfolio
record_format Article
series Communications Biology
spelling doaj.art-37c56c1d42024598a0cbc0976eec86872023-03-22T12:05:36ZengNature PortfolioCommunications Biology2399-36422023-02-016111510.1038/s42003-023-04568-wGlucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteriaThomas J. R. Ormsby0Sian E. Owens1Matthew L. Turner2James G. Cronin3John J. Bromfield4I. Martin Sheldon5Swansea University Medical School, Swansea UniversitySwansea University Medical School, Swansea UniversitySwansea University Medical School, Swansea UniversitySwansea University Medical School, Swansea UniversityDepartment of Animal Sciences, University of FloridaSwansea University Medical School, Swansea UniversityTreating cell lines with glucocorticoids offers protection against the damage caused by subsequent exposure to selected bacterial pore-forming toxins, and is dependent on the glucocorticoid receptor.https://doi.org/10.1038/s42003-023-04568-w
spellingShingle Thomas J. R. Ormsby
Sian E. Owens
Matthew L. Turner
James G. Cronin
John J. Bromfield
I. Martin Sheldon
Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
Communications Biology
title Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
title_full Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
title_fullStr Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
title_full_unstemmed Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
title_short Glucocorticoids increase tissue cell protection against pore-forming toxins from pathogenic bacteria
title_sort glucocorticoids increase tissue cell protection against pore forming toxins from pathogenic bacteria
url https://doi.org/10.1038/s42003-023-04568-w
work_keys_str_mv AT thomasjrormsby glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria
AT sianeowens glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria
AT matthewlturner glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria
AT jamesgcronin glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria
AT johnjbromfield glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria
AT imartinsheldon glucocorticoidsincreasetissuecellprotectionagainstporeformingtoxinsfrompathogenicbacteria