Bicistronic and Stable Expression of Human Coagulation Factor IX and Enhanced Green Fluorescent Protein in Suspension-Adapted Chinese Hamster Ovary Cells

Background and Aim: The current treatment for hemophilia B is replacement therapy, which involves the intravenous infusion of human coagulation factor IX (hFIX) purified from plasma or a recombinant form produced in mammalian cells. In this study, using a bicistronic expression system, the stable ex...

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Bibliographic Details
Main Authors: Fahimeh Ghasemi, Fatemeh Nikumanesh, Alireza Zomorodipour
Format: Article
Language:fas
Published: Kurdistan University of Medical Sciences 2023-05-01
Series:مجله علمی دانشگاه علوم پزشکی کردستان
Subjects:
Online Access:http://sjku.muk.ac.ir/article-1-6344-en.pdf