Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer

Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer

The multistep processes involved in the evolution of inflammation to invasive esophageal squamous cell carcinoma (ESCC) is unclear. Here, the authors report a mouse model of ESCC and the role of interplay between carcinogen-transformed epithelial cells and their microenvironment in ESCC development.

Bibliographic Details
Main Authors: Jiacheng Yao, Qionghua Cui, Wenyi Fan, Yuling Ma, Yamei Chen, Tianyuan Liu, Xiannian Zhang, Yiyi Xi, Chengcheng Wang, Linna Peng, Yingying Luo, Ai Lin, Wenjia Guo, Lin Lin, Yuan Lin, Wen Tan, Dongxin Lin, Chen Wu, Jianbin Wang
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17492-y

Internet

https://doi.org/10.1038/s41467-020-17492-y

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