TRIM44 enhances autophagy via SQSTM1 oligomerization in response to oxidative stress
Abstract The deubiquitinase tripartite motif containing 44 (TRIM44) plays a critical role in linking the proteotoxic stress response with autophagic degradation, which is significant in the context of cancer and neurological diseases. Although TRIM44 is recognized as a prognostic marker in various c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-67832-x |