Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models

Differential Roles of TREM2+ Microglia in Anterograde and Retrograde Axonal Injury Models

Microglia are the main immune cells of the central nervous system (CNS), and they are devoted to the active surveillance of the CNS during homeostasis and disease. In the last years, the microglial receptor Triggering Receptor Expressed on Myeloid cells-2 (TREM2) has been defined to mediate several...

Full description

Bibliographic Details
Main Authors: Gemma Manich, Ariadna Regina Gómez-López, Beatriz Almolda, Nàdia Villacampa, Mireia Recasens, Kalpana Shrivastava, Berta González, Bernardo Castellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
IL-10 (interleukin-10)
IL-6 (interleukin-6)
phagocytosis
proliferation
neuroinflammation
microglial clusters
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.567404/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.567404/full

Similar Items