Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults

Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults

Tanzanian adult male volunteers were immunized by direct venous inoculation with radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (PfSPZ Vaccine) and protective efficacy assessed by homologous controlled human malaria infection (CHMI). Serum immunoglobuli...

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Bibliographic Details
Main Authors: Flavia Camponovo, Joseph J Campo, Timothy Q Le, Amit Oberai, Christopher Hung, Jozelyn V Pablo, Andy A Teng, Xiaowu Liang, B Kim Lee Sim, Said Jongo, Salim Abdulla, Marcel Tanner, Stephen L Hoffman, Claudia Daubenberger, Melissa A Penny
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
PfSPZ Vaccine
protein microarray
humoral immune response
controlled human malaria infection
Online Access:https://elifesciences.org/articles/53080

Internet

https://elifesciences.org/articles/53080

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