Zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway

ETV7 is a human oncoprotein that cooperates with Eμ-MYC to promote pre-B-cell leukemia in mice. It is normally expressed in the bone marrow and fetal liver and is upregulated in primary leukemia, suggesting that it is involved in proper hematopoiesis and leukemogenesis. ETV7 has been deleted in most...

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Bibliographic Details
Main Authors: Anita M. Quintana, Fabrizio Picchione, Ramon I. Klein Geltink, Michael R. Taylor, Gerard C. Grosveld
Format: Article
Language:English
Published: The Company of Biologists 2014-02-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/7/2/265