Linagliptin ameliorated cardiac fibrosis and restored cardiomyocyte structure in diabetic mice associated with the suppression of necroptosis

ABSTRACT Aims/Introduction Linagliptin is a selective dipeptidyl peptidase (DPP)‐4 inhibitor capable of successfully regulating blood glucose levels. The cardiovascular protective effects of several DPP‐4 inhibitors have been shown in preclinical studies; however, the detailed influence of DPP‐4 inh...

Full description

Bibliographic Details
Main Authors: Juthi Adhikari, Taro Hirai, Emi Kawakita, Kunimitsu Iwai, Daisuke Koya, Keizo Kanasaki
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of Diabetes Investigation
Subjects:
Online Access:https://doi.org/10.1111/jdi.14017