JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network

JMJD1C Regulates Megakaryopoiesis in In Vitro Models through the Actin Network

The histone demethylase JMJD1C is associated with human platelet counts. The JMJD1C knockout in zebrafish and mice leads to the ablation of megakaryocyte–erythroid lineage anemia. However, the specific expression, function, and mechanism of JMJD1C in megakaryopoiesis remain unknown. Here, we used ce...

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Bibliographic Details
Main Authors: Jialing Wang, Xiaodan Liu, Haixia Wang, Lili Qin, Anhua Feng, Daoxin Qi, Haihua Wang, Yao Zhao, Lihua Kong, Haiying Wang, Lin Wang, Zhenbo Hu, Xin Xu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
JMJD1C
megakaryopoiesis
cytoskeleton
actin
Ran GTPase
Online Access:https://www.mdpi.com/2073-4409/11/22/3660

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https://www.mdpi.com/2073-4409/11/22/3660

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