Analysis of Human Clinical Mutations of Mitochondrial ND1 in a Bacterial Model System for Complex I
The most common causes of mitochondrial dysfunction and disease include mutations in subunits and assembly factors of Complex I. Numerous mutations in the mitochondrial gene ND1 have been identified in humans. Currently, a bacterial model system provides the only method for rapid construction and an...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Life |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-1729/12/11/1934 |