Protective effects of mitochondrial fission inhibition on ox-LDL induced VSMC foaming via metabolic reprogramming

Atherosclerosis (AS) is one of the most common diseases in middle-age and elderly population. Lipid metabolism disorder induced foaming of vascular smooth muscle cell (VSMC) is an important pathological process of AS. Mitochondria plays an important role in lipids metabolism. While it is not known w...

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Bibliographic Details
Main Authors: Yijin Fang, Yu Zhu, Yue Wu, Liangming Liu, Huadong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.970151/full