Neuroprotective Activity of Some Marine Fungal Metabolites in the 6-Hydroxydopamin- and Paraquat-Induced Parkinson’s Disease Models

Neuroprotective Activity of Some Marine Fungal Metabolites in the 6-Hydroxydopamin- and Paraquat-Induced Parkinson’s Disease Models

A new melatonin analogue 6-hydroxy-<i>N</i>-acetyl-&#946;-oxotryptamine (<b>1</b>) was isolated from the marine-derived fungus <i>Penicillium</i> sp. KMM 4672. It is the second case of melatonin-related compounds isolation from microfilamentous fungi. The neur...

Full description

Bibliographic Details
Main Authors: Ekaterina A. Yurchenko, Ekaterina S. Menchinskaya, Evgeny A. Pislyagin, Phan Thi Hoai Trinh, Elena V. Ivanets, Olga F. Smetanina, Anton N. Yurchenko
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Marine Drugs
Subjects:
neuroprotective activity
Parkinson’s disease
ROS
DPPH-scavenging activity
6-OHDA
paraquat
marine fungal metabolites
Online Access:https://www.mdpi.com/1660-3397/16/11/457

Internet

https://www.mdpi.com/1660-3397/16/11/457

Similar Items