Hydrogen Sulfide Inhibits Abnormal Proliferation of Lymphocytes via AKT/GSK3β Signal Pathway in Systemic Lupus Erythematosus Patients

Hydrogen Sulfide Inhibits Abnormal Proliferation of Lymphocytes via AKT/GSK3β Signal Pathway in Systemic Lupus Erythematosus Patients

Background/Aim: The abnormal activation of the AKT/GSK3β signal pathway in lymphocytes from systemic lupus erythematosus (SLE) patients plays an important role in the pathogenesis of the disease. Recently Hydrogen sulfide (H2S) has been recognized as a crucial gaseous signaling molecule, involved in...

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Bibliographic Details
Main Authors: Yanfang Han, Fanqin Zeng, Guozhen Tan, Chuntao Yang, Hongfeng Tang, Yijin Luo, Jianqiang Feng, Hui Xiong, Qing Guo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
AKT
GSK3β
Cell cycle
Hydrogen sulfide
Lymphocytes
Systemic lupus erythematosus
Online Access:http://www.karger.com/Article/FullText/350097

Internet

http://www.karger.com/Article/FullText/350097

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